DocumentCode
1532625
Title
Magnetophoresis of diamagnetic cells and microorganisms in a culture medium
Author
Iwasaka, Masakazu ; Miyakoshi, Junji ; Ueno, Shoogo
Author_Institution
Dept. of Biomed. Eng., Tokyo Univ., Japan
Volume
37
Issue
4
fYear
2001
fDate
7/1/2001 12:00:00 AM
Firstpage
2644
Lastpage
2646
Abstract
In the present study, the magnetophoresis of three types of diamagnetic cells was observed under gradient magnetic fields. The predicted mechanism of the cell´s magnetophoresis, the drifting of cells in gradient magnetic fields, was attributable to the difference in the diamagnetic forces on water and the cell. The spatial density gradient of the cells, which resulted from the magnetophoresis, was measured by an optical transmission measurement after exposure to magnetic fields of 9-14 T with a maximum gradient of 94 T/m. In the case of smooth muscle cells, adherent cells, the long-term and short-term digestion of cells by the enzyme trypsin resulted in an increased cell density distribution under high magnetic fields and an increase under low magnetic fields, respectively. In the experiments with yeast and blood platelets, the cells moved downward to the lower magnetic fields in the chamber, and a visible density distribution change was observed
Keywords
biological effects of fields; biomagnetism; cellular transport; diamagnetic materials; microorganisms; 9 to 14 T; adherent cell; blood platelet; cell density distribution; cell digestion; culture medium; diamagnetic cell; gradient magnetic field; magnetophoresis; microorganism; optical transmission; smooth muscle cell; trypsin enzyme; yeast; Blood; Cells (biology); Fungi; Magnetic field measurement; Magnetic fields; Magnetic levitation; Magnetic separation; Microorganisms; Muscles; Superconducting magnets;
fLanguage
English
Journal_Title
Magnetics, IEEE Transactions on
Publisher
ieee
ISSN
0018-9464
Type
jour
DOI
10.1109/20.951261
Filename
951261
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