DocumentCode
1532853
Title
Three-Class ROC Analysis—Toward a General Decision Theoretic Solution
Author
He, Xin ; Gallas, Brandon D. ; Frey, Eric C.
Author_Institution
Sch. of Med., Dept. of Radiol., Johns Hopkins Univ., Baltimore, MD, USA
Volume
29
Issue
1
fYear
2010
Firstpage
206
Lastpage
215
Abstract
Multiclass receiver operating characteristic (ROC) analysis has remained an open theoretical problem since the introduction of binary ROC analysis in the 1950s. Previously, we have developed a paradigm for three-class ROC analysis that extends and unifies decision theoretic, linear discriminant analysis, and probabilistic foundations of binary ROC analysis in a three-class paradigm. One critical element in this paradigm is the equal error utility (EEU) assumption. This assumption allows us to reduce the intrinsic space of the three-class ROC analysis (5-D hypersurface in 6-D hyperspace) to a 2-D surface in the 3-D space of true positive fractions (sensitivity space). In this work, we show that this 2-D ROC surface fully and uniquely provides a complete descriptor for the optimal performance of a system for a three-class classification task, i.e., the triplet of likelihood ratio distributions, assuming such a triplet exists. To be specific, we consider two classifiers that utilize likelihood ratios, and we assumed each classifier has a continuous and differentiable 2-D sensitivity-space ROC surface. Under these conditions, we proved that the classifiers have the same triplet of likelihood ratio distributions if and only if they have the same 2-D sensitivity-space ROC surfaces. As a result, the 2-D sensitivity surface contains complete information on the optimal three-class task performance for the corresponding likelihood ratio classifier.
Keywords
biomedical imaging; decision theory; sensitivity analysis; 5D hypersurface; 6D hyperspace; decision theoretic solution; equal error utility; likelihood ratio distribution; receiver operating characteristic analysis; three class ROC analysis; three class paradigm; Biomedical imaging; Linear discriminant analysis; Malignant tumors; Mammography; Medical diagnosis; Medical diagnostic imaging; Myocardium; Neoplasms; Radiology; Extended receiver operating characteristic (ROC) analysis; ROC analysis; three-class ROC analysis; Algorithms; Decision Support Techniques; Diagnostic Imaging; Humans; Image Processing, Computer-Assisted; ROC Curve;
fLanguage
English
Journal_Title
Medical Imaging, IEEE Transactions on
Publisher
ieee
ISSN
0278-0062
Type
jour
DOI
10.1109/TMI.2009.2034516
Filename
5306177
Link To Document