DocumentCode
1535612
Title
Ideal observer approximation using Bayesian classification neural networks
Author
Kupinski, Matthew A. ; Edwards, Darrin C. ; Giger, Maryellen L. ; Metz, Charles E.
Author_Institution
Dept. of Radiol., Chicago Univ., IL, USA
Volume
20
Issue
9
fYear
2001
Firstpage
886
Lastpage
899
Abstract
It is well understood that the optimal classification decision variable is the likelihood ratio or any monotonic transformation of the likelihood ratio. An automated classifier which maps from an input space to one of the likelihood ratio family of decision variables is an optimal classifier or "ideal observer." Artificial neural networks (ANNs) are frequently used as classifiers for many problems. In the limit of large training sample sizes, an ANN approximates a mapping function which is a monotonic transformation of the likelihood ratio, i.e., it estimates an ideal observer decision variable. A principal disadvantage of conventional ANNs is the potential over-parameterization of the mapping function which results in a poor approximation of an optimal mapping function for smaller training samples. Recently, Bayesian methods have been applied to ANNs in order to regularize training to improve the robustness of the classifier. The goal of training a Bayesian ANN with finite sample sizes is, as with unlimited data, to approximate the ideal observer. The authors have evaluated the accuracy of Bayesian ANN models of ideal observer decision variables as a function of the number of hidden units used, the signal-to-noise ratio of the data and the number of features or dimensionality of the data. The authors show that when enough training data are present, excess hidden units do not substantially degrade the accuracy of Bayesian ANNs. However, the minimum number of hidden units required to best model the optimal mapping function varies with the complexity of the data.
Keywords
Bayes methods; image classification; medical image processing; neural nets; observers; Bayesian classification neural networks; artificial neural networks; automated classifier; computer-aided diagnosis; data complexity; ideal observer approximation; ideal observer decision variables; large training sample sizes; likelihood ratio; medical diagnostic imaging; monotonic transformation; optimal classifier; optimal mapping function; Artificial neural networks; Bayesian methods; Computer aided diagnosis; Degradation; Diseases; Neural networks; Radiology; Robustness; Signal to noise ratio; Training data; Bayes Theorem; Diagnosis, Computer-Assisted; Humans; Neural Networks (Computer); ROC Curve;
fLanguage
English
Journal_Title
Medical Imaging, IEEE Transactions on
Publisher
ieee
ISSN
0278-0062
Type
jour
DOI
10.1109/42.952727
Filename
952727
Link To Document