• DocumentCode
    1535612
  • Title

    Ideal observer approximation using Bayesian classification neural networks

  • Author

    Kupinski, Matthew A. ; Edwards, Darrin C. ; Giger, Maryellen L. ; Metz, Charles E.

  • Author_Institution
    Dept. of Radiol., Chicago Univ., IL, USA
  • Volume
    20
  • Issue
    9
  • fYear
    2001
  • Firstpage
    886
  • Lastpage
    899
  • Abstract
    It is well understood that the optimal classification decision variable is the likelihood ratio or any monotonic transformation of the likelihood ratio. An automated classifier which maps from an input space to one of the likelihood ratio family of decision variables is an optimal classifier or "ideal observer." Artificial neural networks (ANNs) are frequently used as classifiers for many problems. In the limit of large training sample sizes, an ANN approximates a mapping function which is a monotonic transformation of the likelihood ratio, i.e., it estimates an ideal observer decision variable. A principal disadvantage of conventional ANNs is the potential over-parameterization of the mapping function which results in a poor approximation of an optimal mapping function for smaller training samples. Recently, Bayesian methods have been applied to ANNs in order to regularize training to improve the robustness of the classifier. The goal of training a Bayesian ANN with finite sample sizes is, as with unlimited data, to approximate the ideal observer. The authors have evaluated the accuracy of Bayesian ANN models of ideal observer decision variables as a function of the number of hidden units used, the signal-to-noise ratio of the data and the number of features or dimensionality of the data. The authors show that when enough training data are present, excess hidden units do not substantially degrade the accuracy of Bayesian ANNs. However, the minimum number of hidden units required to best model the optimal mapping function varies with the complexity of the data.
  • Keywords
    Bayes methods; image classification; medical image processing; neural nets; observers; Bayesian classification neural networks; artificial neural networks; automated classifier; computer-aided diagnosis; data complexity; ideal observer approximation; ideal observer decision variables; large training sample sizes; likelihood ratio; medical diagnostic imaging; monotonic transformation; optimal classifier; optimal mapping function; Artificial neural networks; Bayesian methods; Computer aided diagnosis; Degradation; Diseases; Neural networks; Radiology; Robustness; Signal to noise ratio; Training data; Bayes Theorem; Diagnosis, Computer-Assisted; Humans; Neural Networks (Computer); ROC Curve;
  • fLanguage
    English
  • Journal_Title
    Medical Imaging, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0278-0062
  • Type

    jour

  • DOI
    10.1109/42.952727
  • Filename
    952727