Title :
Force-distance curves by AFM
Author :
Cappella, B. ; Baschieri, P. ; Frediani, C. ; Miccoli, P. ; Ascoli, C.
Author_Institution :
Ist. di Biofisica, CNR, Pisa, Italy
Abstract :
Since 1989, the atomic force microscope (AFM) has emerged as a useful tool in studying surface interactions by means of force-distance curves, and a great deal of work has been carried out on both its theoretical and experimental issues. AFM is able to acquire force-distance curves from every kind of surface, with high lateral (1 Å), vertical (0.1 Å) and force (1 pN) resolution. Moreover, the study of force-distance curves provides a deeper knowledge of the physics of contact, and hence of all the phenomena connected with AFM imaging techniques. In this article, we review force-distance curve theory, and show through curves acquired with a home-made microscope the main surface interactions that can be revealed.
Keywords :
adhesion; adsorption; atomic force microscopy; biological techniques; reviews; surface energy; van der Waals forces; AFM; AFM imaging techniques; aqueous solutions; atomic force microscope; force-distance curve theory; force-distance curves; home-made microscope; liquids; octamethylcyclotetrasiloxane; physics of contact; surface interactions; van der Waals force; Atomic force microscopy; Biomedical engineering; Equations; Force control; Force measurement; Hysteresis; Position measurement; Adsorption; Air; Aluminum Silicates; Elasticity; Electrolytes; Ethanol; Formamides; Gold; Hydrogen-Ion Concentration; Materials Testing; Microscopy, Atomic Force; Siloxanes; Surface Properties; Water;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE