Tomographic radiopharmaceutical imaging

Author

Jasczak, R.J.

Author_Institution

Dept. of Radiol./Nucl. Med., Duke Univ. Med. Center, Durham, NC

Volume

76

Issue

9

fYear

1988

fDate

9/1/1988 12:00:00 AM

Firstpage

1079

Lastpage

1094

Abstract

Tomographic radiopharmaceutical imaging, or emission computed tomography (ECT), provides in vivo three-dimensional maps of a pharmaceutical labeled with a gamma-ray-emitting radionuclide. ECT has developed in two complimentary directions based on the type of radionuclide that is used. Positron emission computed tomography (PET) detects the two coincident 511-keV annihilation photos from position emitters such as ¹¹C, ¹³N, ¹⁵O, and ¹⁸F. Single-photon-emission computed tomography (SPECT) involves detection of gamma rays emitted singly, and sequentially, by the radionuclide tracer. The author presents examples of PET and SPECT imaging devices and reviews a widely used reconstruction algorithm. Current research areas that are under active investigation are also described

Keywords

computerised tomography; radioisotope scanning and imaging; reviews; 511 keV; ¹¹C; ¹³N; ¹⁵O; ¹⁸F; PET; SPECT; emission computed tomography; in vivo 3D maps; nuclear medicine; reconstruction algorithm; single-photon-emission computed tomography; tomographic radiopharmaceutical imaging; Computed tomography; Electrical capacitance tomography; Gamma ray detection; Gamma ray detectors; Gamma rays; In vivo; Optical imaging; Pharmaceuticals; Positron emission tomography; Radioactive decay;

fLanguage

English

Journal_Title

Proceedings of the IEEE

Publisher

ieee

ISSN

0018-9219

Type

jour

DOI

10.1109/5.9654

Filename

9654