Title :
Evaluation of the TierPET system
Author :
Weber, S. ; Herzog, H. ; Cremer, M. ; Engels, R. ; Hamacher, K. ; Kehren, E. ; Muehlensiepen, H. ; Ploux, L. ; Reinartz, R. ; Reinhart, P. ; Rongen, E. ; Sonnenberg, E. ; Coenen, H.H. ; Halling, H.
Author_Institution :
Forschungszentrum Julich GmbH, Germany
fDate :
8/1/1999 12:00:00 AM
Abstract :
The TierPET system, a high resolution 3D positron emission tomograph, has been developed to perform small animal positron emission tomography (PET) studies. High resolution PET opens the possibility to perform animal trials without the need for vivisection. This reduces the number of animals and the costs for such experiments, for example concerning the development of new radiopharmaceuticals. The scanner uses two orthogonal pairs of detectors consisting of arrays of small individual YAP crystals coupled to position sensitive photomultipliers. The center-detector distance may be varied to improve either sensitivity or spatial resolution. The spatial resolution of the scanner is 2.1 mm
Keywords :
biological techniques; biomedical equipment; image resolution; photomultipliers; positron emission tomography; 2.1 mm; TierPET system evaluation; YAP; YAlO3; animal trials; high resolution 3D positron emission tomograph; medical instrumentation; new radiopharmaceuticals development; orthogonal detectors pairs; position sensitive photomultipliers; sensitivity; small animal positron emission tomography studies; small individual YAP crystals arrays; spatial resolution; vivisection; Animals; Costs; Detectors; Drugs; Optical scattering; Photomultipliers; Photonic crystals; Positron emission tomography; Spatial resolution; Transmission line matrix methods;
Journal_Title :
Nuclear Science, IEEE Transactions on
