Design of an integrated potentiostat circuit for CMOS bio sensor chips

Author

Frey, Alexander ; Jenkner, Martin ; Schienle, Meinrad ; Paulus, Christian ; Holzapfl, Birgit ; Schindler-Bauer, Petra ; Hofmann, Franz ; Kuhlmeier, D. ; Krause, Jürgen ; Albers, Jorg ; Gumbrecht, Walter ; Schmitt-Landsiedel, Doris ; Thewes, Roland

Author_Institution

Corporate Res., Infineon Technol. AG, Munich, Germany

Volume

5

fYear

2003

Abstract

A design strategy is presented for potentiostat circuits suitable for electronic bio sensors on CMOS. Guidelines are given to guarantee stable operation under the condition of widely varying and only roughly known electrochemical parameters. A concrete design example used in a fully electronic DNA sensor array CMOS chip is shown. Measurement results with a biological analyte applied to that chip prove proper operation of the potentiostat.

Keywords

CMOS integrated circuits; DNA; biosensors; circuit stability; electrochemical analysis; integrated circuit design; integrated circuit measurement; CMOS biosensor chips; DNA sensor array; biological analyte; circuit stability; electrochemical parameters; folded cascode amplifier; integrated potentiostat circuit; Biomedical optical imaging; Biosensors; Consumer electronics; Counting circuits; DNA; Electrodes; Optical arrays; Optical sensors; Semiconductor device measurement; Sensor arrays;

fLanguage

English

Publisher

ieee

Conference_Titel

Circuits and Systems, 2003. ISCAS '03. Proceedings of the 2003 International Symposium on

Print_ISBN

0-7803-7761-3

Type

conf

DOI

10.1109/ISCAS.2003.1206159

Filename

1206159