RAPTOR: a fluoroimmunoassay-based fiber optic sensor for detection of food pathogens

Author

Jung, C. ; McCrae, D.A. ; Saaski, E.W. ; DeMarco, D.R. ; Lim, D.V.

Author_Institution

Res. Int., Woodinville, WA, USA

fYear

2002

Firstpage

249

Abstract

This paper describes a portable, 4-channel fluorescence-based immunoassay system called "RAPTOR", which has been developed by Research International in conjunction with the Naval Research Laboratory. The RAPTOR represents a careful integration of optics, fluidics, electronics, and software into one compact system. This unit can automatically perform a user-defined, multi-step assay while simultaneously recording the signal from fluorescently-conjugated reporter antibodies as they bind to the surface of each of the system\´s four optical waveguides located in the disposable injection molded coupon. The RAPTOR can be used for high-sensitivity monitoring of biological agents and toxins in the lab or in the field.

Keywords

biosensors; fibre optic sensors; fluorescence; microorganisms; monitoring; optical waveguides; E. coli; Escherichia coli; RAPTOR; biological agents; biological toxins; compact system; disposable injection molded coupon; fiber optic biosensor; fluorescently-conjugated reporter antibodies; fluoroimmunoassay-based fiber optic sensor; food pathogens detection; high-sensitivity monitoring; injection-molded polystyrene waveguides; optical waveguides; portable 4-channel system; user-defined multi-step assay; Biomedical optical imaging; Fluorescence; Immune system; Laboratories; Optical detectors; Optical fiber sensors; Optical recording; Optical sensors; Optical waveguides; Pathogens;

fLanguage

English

Publisher

ieee

Conference_Titel

Optical Fiber Sensors Conference Technical Digest, 2002. Ofs 2002, 15th

Conference_Location

Portland, OR, USA

Print_ISBN

0-7803-7289-1

Type

conf

DOI

10.1109/OFS.2002.1000548

Filename

1000548