DocumentCode :
1566593
Title :
Protein ontology: vocabulary for protein data
Author :
Sidhu, Amandeep S. ; Dillon, Tharam S. ; Chang, Elizabeth ; Sidhu, Baldev S.
Author_Institution :
Fac. of Inf. Technol., Technol. Univ., Sydney, NSW, Australia
Volume :
1
fYear :
2005
Firstpage :
465
Abstract :
These huge amounts of protein structure data make it difficult to create explanatory and predictive models that are consistent with huge volume of data. Difficulty increase when large variety of heterogeneous approaches gathers data from multiple perspectives. In order to facilitate computational processing data, it is especially critical to develop standardized structured data representation model formats for proteomics data. In this paper, we describe a protein ontology model for integrating protein databases and deduce a structured vocabulary for understanding process of protein synthesis completely. Proposed protein ontology model provides biologists and scientists with a description of sequence, structure and functions of protein and also provides interpretation of various factors on final protein structure conformation. The structured vocabulary for protein data, describing protein ontology is composed of various type definitions for protein entry details, sequence and structural information of proteins, structural domain family of protein, cellular function of protein, chemical bonds present in the protein, and external constraints deciding final protein conformation. The proposed ontology model will provide easier ways to predict and understand proteins.
Keywords :
biology computing; database management systems; ontologies (artificial intelligence); proteins; biomedical ontologies; biomedical systems; chemical bonds; data integration; predictive model; protein cellular function; protein databases; protein entry detail; protein informatics; protein ontology model; protein sequences; protein structural domain family; protein structural information; protein structure data; systems biology; Biological system modeling; Biology computing; Databases; Evolution (biology); Ontologies; Prediction methods; Predictive models; Proteins; Sequences; Vocabulary; Biomedical Ontologies; Biomedical Systems; Data Integration; Protein Informatics; Protein Ontology; Systems Biology;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Information Technology and Applications, 2005. ICITA 2005. Third International Conference on
Print_ISBN :
0-7695-2316-1
Type :
conf
DOI :
10.1109/ICITA.2005.223
Filename :
1488849
Link To Document :
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