Title :
Investigation of hemolysis in a generic implantable device: An FDA initiative
Author :
Sirois, Eric ; Sun, Wei
Author_Institution :
Univ. of Connecticut, Storrs, CT
Abstract :
Computational fluid simulations were developed for a generic blood-interfacing implantable device. The simulations were analyzed to determine hemodynamic behavior within the device, including velocity profiles, the magnitude of shear stress, and pressure drop. By monitoring 100 streamlines, the total blood damage induced by the device was estimated and compared to that observed for a bioprosthetic aortic valve.
Keywords :
biomedical equipment; blood; haemodynamics; prosthetics; shear strength; velocity; FDA initiative; bioprosthetic aortic valve; computational fluid simulation; generic blood-interfacing implantable device; hemodynamic behavior determination; hemolysis; pressure drop; shear stress magnitude; streamline; total blood damage estimation; Analytical models; Atmospheric modeling; Computational fluid dynamics; Computational modeling; Equations; Geometry; Hemodynamics; Neck; Stress; Valves; Biomechanics; Biomedical; Computational Fluid Dynamics; Engineering; Hemolysis;
Conference_Titel :
Bioengineering Conference, 2009 IEEE 35th Annual Northeast
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4362-8
Electronic_ISBN :
978-1-4244-4364-2
DOI :
10.1109/NEBC.2009.4967732
