Title :
Single-walled carbon nanotube facilitated photoacoustic stimulation of marrow stromal cells towards osteoblasts
Author :
Green, Danielle E. ; Longtin, Jon P. ; Sitharaman, Balaji
Author_Institution :
Dept. of Biomed. Eng., State Univ. of New York at Stony Brook, Stony Brook, NY
Abstract :
The ability to control marrow stromal cell (MSC) differentiation towards osteoblasts could potentially play a key role in bone regeneration. Here we examine the efficacy of the photoacoustic (PA) effect enhanced by the presence of single-walled carbon nanotubes (SWNTs) on the differentiation of MSCs. We report that MSCS in the presence or absence of SWNTs exposed to brief PA stimulation (10 mins daily) using a nanosecond pulse-laser over a period 16 consecutive days have increased osteodifferentiation.
Keywords :
bioacoustics; bone; carbon nanotubes; cellular biophysics; laser applications in medicine; photoacoustic effect; MSC differentiation; bone regeneration; marrow stromal cell; nanosecond pulse-laser; osteoblast; photoacoustic stimulation; single-walled carbon nanotube; time 16 day; Acoustic beams; Acoustic pulses; Biomedical engineering; Bones; Carbon nanotubes; Laser beams; Laser theory; Optical pulses; Pulsed laser deposition; Stem cells; Single-walled carbon nanotube; bone regeneration; osteoblasts; photoacoustic effect; pulse-laser;
Conference_Titel :
Bioengineering Conference, 2009 IEEE 35th Annual Northeast
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4362-8
Electronic_ISBN :
978-1-4244-4364-2
DOI :
10.1109/NEBC.2009.4967736
