• DocumentCode
    1568548
  • Title

    Phase transition and particle formation of a Human Elastin-Like polypeptide

  • Author

    Bandiera, A. ; Sist, P. ; Terdoslavich, M. ; Urbani, R.

  • Author_Institution
    Dept. of Life Sci., Univ. of Trieste, Trieste
  • fYear
    2009
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Elastin-Like Polypeptides are an interesting class of recombinant proteins that mimic elastin. Here we present some data about phase transition properties and particle formation features of the recombinantly expressed Human Elastin-Like polypeptide (HELP). This macromolecule shows a promising potential as vehicle for delivery and controlled release of active compounds.
  • Keywords
    macromolecules; molecular biophysics; proteins; HELP; active molecule controlled release; active molecule delivery; macromolecules; particle formation feature; phase transition properties; recombinant proteins; recombinantly expressed human elastin-like polypeptide; Aggregates; Biodegradable materials; Cooling; Degradation; Humans; Peptides; Protein engineering; Self-assembly; Temperature; Vehicles;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference, 2009 IEEE 35th Annual Northeast
  • Conference_Location
    Boston, MA
  • Print_ISBN
    978-1-4244-4362-8
  • Electronic_ISBN
    978-1-4244-4364-2
  • Type

    conf

  • DOI
    10.1109/NEBC.2009.4967772
  • Filename
    4967772