Title :
Phase transition and particle formation of a Human Elastin-Like polypeptide
Author :
Bandiera, A. ; Sist, P. ; Terdoslavich, M. ; Urbani, R.
Author_Institution :
Dept. of Life Sci., Univ. of Trieste, Trieste
Abstract :
Elastin-Like Polypeptides are an interesting class of recombinant proteins that mimic elastin. Here we present some data about phase transition properties and particle formation features of the recombinantly expressed Human Elastin-Like polypeptide (HELP). This macromolecule shows a promising potential as vehicle for delivery and controlled release of active compounds.
Keywords :
macromolecules; molecular biophysics; proteins; HELP; active molecule controlled release; active molecule delivery; macromolecules; particle formation feature; phase transition properties; recombinant proteins; recombinantly expressed human elastin-like polypeptide; Aggregates; Biodegradable materials; Cooling; Degradation; Humans; Peptides; Protein engineering; Self-assembly; Temperature; Vehicles;
Conference_Titel :
Bioengineering Conference, 2009 IEEE 35th Annual Northeast
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4362-8
Electronic_ISBN :
978-1-4244-4364-2
DOI :
10.1109/NEBC.2009.4967772
