DocumentCode :
15703
Title :
Rapid electronic prediction of gene expression regulation in bacterial cells
Author :
Alam, Shahinur ; Lai, E.M.-K. ; Young, James ; Hasan, S. M. Rezaul
Author_Institution :
Sch. of Eng. & Adv. Technol., Massey Univ., Auckland, New Zealand
Volume :
50
Issue :
22
fYear :
2014
fDate :
10 23 2014
Firstpage :
1566
Lastpage :
1568
Abstract :
A cytomorphic circuit that can mimic gene expression regulation mechanisms is presented. It is shown that this circuit can efficiently predict the cellular response of the bacterium Escherichia coli in real time. The simulation outputs of the circuit are compared with biological experimental results. The significant similarity between these results shows that the circuit can be used to predict cellular malfunctioning within microseconds.
Keywords :
cellular biophysics; genetics; microorganisms; Escherichia coli bacterium; bacterial cells; cellular malfunctioning; cellular response; cytomorphic circuit; gene expression regulation; microseconds; rapid electronic prediction; real time;
fLanguage :
English
Journal_Title :
Electronics Letters
Publisher :
iet
ISSN :
0013-5194
Type :
jour
DOI :
10.1049/el.2014.2144
Filename :
6937285
Link To Document :
بازگشت