Title :
Manufacture and Characterisation of a Bioactive and Biodegradable Composite Developed for Bone Tissue Repair
Author :
Liu, Ya ; Wang, Min
Author_Institution :
Dept. of Mech. Eng., Hong Kong Univ.
Abstract :
A bioactive and biodegradable composite containing hydroxyapatite (HA) and polyhydroxybutyrate (PHB) was developed for bone tissue repair. A manufacturing process, which consisted of compounding, pelletising, drying, and injection moulding, was established for producing the composite. The HA/PHB composite containing 10, 20, 30 and 40% by volume of particulate HA was successfully made. The distribution of HA particles in the PHB matrix was examined using scanning electron microscopy (SEM). Differential scanning calorimetry (DSC) was employed to investigate the melting and crystallization behavior of both compounded and injection moulded HA/PHB composite
Keywords :
biomedical materials; bone; calcium compounds; cellular biophysics; crystallisation; differential scanning calorimetry; drying; filled polymers; injection moulding; melting; particle reinforced composites; scanning electron microscopy; tissue engineering; bioactive composite; biodegradable composite; bone tissue repair; compounding; crystallization; differential scanning calorimetry; drying; hydroxyapatite; injection moulding; melting; pelletising; polyhydroxybutyrate; scanning electron microscopy; Biodegradable materials; Biological materials; Bone tissue; Crystalline materials; Crystallization; Injection molding; Manufacturing; Matrices; Raw materials; Scanning electron microscopy;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1615365
