Title :
A low power 100MΩ CMOS front-end transimpedance amplifier for biosensing applications
Author :
Hu, Jiaping ; Kim, Yong-Bin ; Ayers, Joseph
Author_Institution :
Dept. of Electr. & Comput. Eng., Northeastern Univ., Boston, MA, USA
Abstract :
In this paper, the design, implementation and simulation of a high-gain, low-power, low-noise CMOS front-end transimpedance amplifier (TIA) is presented for interfacing with a bio-sensor array and analog neural circuits. An improved capacitive-feedback TIA topology is used with an active load to obtain a 100MΩ transimpedance gain, 1MHz bandwidth, 158fA/rt(Hz) input-referred current noise at sensing frequency, near 0° phase shift and 1V peak-to-peak output swing. The proposed circuit dissipates 132μW from a 1.8V supply and the circuit is implemented in a standard 0.18μm CMOS 1P6M technology.
Keywords :
CMOS integrated circuits; biosensors; operational amplifiers; CMOS front-end transimpedance amplifier; analog neural circuits; bio-sensor array; capacitive-feedback TIA topology; input-referred current noise; power 132 muW; resistance 100 Mohm; size 0.18 mum; transimpedance gain; voltage 1.8 V; Active noise reduction; Bandwidth; Biosensors; CMOS analog integrated circuits; CMOS technology; Circuit noise; Circuit simulation; Circuit topology; Low-noise amplifiers; Phase noise;
Conference_Titel :
Circuits and Systems (MWSCAS), 2010 53rd IEEE International Midwest Symposium on
Conference_Location :
Seattle, WA
Print_ISBN :
978-1-4244-7771-5
DOI :
10.1109/MWSCAS.2010.5548884
