Title :
Monitoring System of Cell´s Viability and Function for Bioartificial Liver Support System
Author :
Lou, Hanfen ; Li, Ming ; Xiang, Hongsheng ; Liu, Jianfeng ; Yang, Wei
Author_Institution :
Inst. of Electr. Eng., Chinese Acad. of Sci., Beijing
Abstract :
This paper aims to develop an online cell monitoring system for rapid understanding the cell´s viability and functional activity, hence appropriate measures could be adopted in time. Traditional off line technique was changed into online monitoring in this instrument for rapidly detecting albumin and urea. Monocolor light source and integrated photoelectric sensor were adopted in this system. It was demonstrated in experiment that this system was designed of a novel and simple construction, which could fulfil the requirements of measuring the cell´s functional activity in bioartificial liver. This design is proved feasible and reliable. It provides a novel system to monitor cell´s viability and function on line quickly. Using this monitoring system, the closed-loop controlling of bioartificial liver support system can be realized
Keywords :
artificial organs; bio-optics; bioelectric phenomena; biomedical measurement; cellular biophysics; electric sensing devices; molecular biophysics; optical sensors; patient monitoring; photoelectric devices; proteins; albumin; bioartificial liver support system; cell function; cell viability; integrated photoelectric sensor; monocolor light source; online cell monitoring system; urea; Bioreactors; Filters; Light emitting diodes; Light sources; Liver; Optical amplifiers; Patient monitoring; Photoelectricity; Photometry; Temperature sensors; Bioartificial liver support system; albumin; cell monitor; light emitting diode; urea;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616013
