Title :
Atmospheric pressure cold plasma leads to apoptosis in saccharomyces cerevisiae by accumulation of intracellular reactive oxygen species and calcium
Author :
Ruonan Ma ; Ying Tian ; Qian Zhang ; Jing Fang ; Jue Zhang ; Hongqing Feng ; Yongdong Liang
Author_Institution :
Acad. for Adv. Interdiscipl. Studies, Peking Univ., Beijing, China
Abstract :
Applications of atmospheric pressure cold plasma have been extended to various cancers therapy due to plasma-produced reactive oxygen species (ROS) inducing oxidative stress in cancer cell and consequently resulting in cell apoptosis. However, the mechanism of apoptosis caused by plasma is complicated. Actually, besides various kinds of intracellular ROS, calcium (Ca2t) also plays a critical role in apoptosis process.
Keywords :
cancer; cellular biophysics; microorganisms; oxygen; plasma applications; plasma interactions; radiation therapy; O2; ROS; Saccharomyces Cerevisiae; atmospheric pressure cold plasma; cancer cell; cancer therapy; cell apoptosis; oxidative stress; plasma-produced reactive oxygen species; Biomembranes; Calcium; Cancer; Educational institutions; Fluorescence; Plasma measurements; Plasmas;
Conference_Titel :
Plasma Science (ICOPS), 2013 Abstracts IEEE International Conference on
Conference_Location :
San Francisco, CA
DOI :
10.1109/PLASMA.2013.6634816
