Title :
Computer model of cardiac diastolic dynamics
Author :
Summers, RL ; Montani, Jp
Author_Institution :
Dept. of Physiol., Mississippi Univ. Med. Center, Jackson, MS, USA
Abstract :
A dynamic model of diastolic pressure (DP/dt) was derived from basic biophysical principles for use in a systems analysis of circulatory blood flow. In the model, DP/dt is considered to be biphasic in nature and of the general mathematical form DP/dt f(R , Q) where R (ventricular relaxation rate) controls the isovolemic relaxation phase and Q (flow into the ventricle) determines the pressure during the diastolic filling period. When the model is incorporated into a general cardiovascular model it can be used in computer simulation studies to analyze the effects of changes in parameters such as diastolic ventricular compliance and relaxation time on overall circulatory blood flow
Keywords :
biology computing; cardiology; digital simulation; haemodynamics; physiological models; basic biophysical principles; cardiac diastolic dynamics; circulatory blood flow; diastolic filling period; diastolic pressure; dynamic model; haemodynamic model; isovolemic relaxation phase; systems analysis; ventricular flow; ventricular relaxation rate; Blood flow; Computer simulation; Filling; Immune system; Mathematical model; Muscles; Physiology; Pressure control; Stress; Virtual reality;
Conference_Titel :
Computers in Cardiology 1992, Proceedings of
Conference_Location :
Durham, NC
Print_ISBN :
0-8186-3552-5
DOI :
10.1109/CIC.1992.269543
