Title :
An Image-Based Approach to Measure the Ferric Ion Diffusion Coefficient in Fricke Gel Dosimetry
Author :
Tseng, Y.J. ; Huang, Sung-Cheng ; Chu, W.C.
Author_Institution :
Inst. of Biomed. Eng., Nat. Yang Ming Univ., Taipei
Abstract :
A numerical method was adopted to solve the diffusion equation to determine ferric ion diffusion coefficient in Fricke-agarose gels. A fast MR acquisition technique was employed to avoid smearing of acquired data due to diffusion over an extended time period. Our results show that for a Fricke gel contained 1 mM ammonium ferrous sulfate, 1% agarose, 1 nM sodium chloride and 50 mM sulfuric acid, its ferric ion diffusion coefficient is 1.73times10-2 cm2h-1 in room temperature. This value is consistent with the 1 ~ 2times10-2 cm2h-1 range obtained by previous studies under varying concentrations of gel ingredients
Keywords :
biodiffusion; biomedical MRI; dosimetry; gels; Fricke gel dosimetry; Fricke-agarose gels; MR acquisition technique; ferric ion diffusion coefficient; image-based approach; Biomedical engineering; Biomedical imaging; Biomedical measurements; Difference equations; Differential equations; Dosimetry; Laplace equations; Physics; Tellurium; Temperature; Fricke-infused gel dosimetry; explicit method; ferric ion diffusion coefficient; radiation dosimetry;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616220
