Title :
A Causal Discovery Approach to Identifying Active Components of Herbal Medicine
Author :
Wang, Yi ; Wang, Xuewei ; Cheng, Yiyu
Author_Institution :
Coll. of Pharm. Sci., Zhejiang Univ., Hangzhou
Abstract :
In the present study, a stepwise causal adjacent relationship discovery (STEPCARD) method has been developed to identify active components of herbal medicine. The combination of two active components had been successfully recognized from a typical Chinese formulation. Animal experiments validated the computational result. It indicates current work might be helpful to accelerate the process of new drug discovery from herbal medicine
Keywords :
chemical analysis; drugs; medical computing; STEPCARD; active components identification; drug discovery; herbal medicine; stepwise causal adjacent relationship discovery; Acceleration; Animals; Biology computing; Chemical compounds; Drugs; Educational institutions; Electronic mail; Pharmaceuticals; Statistical analysis; Testing;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616301