The Multifocal ERG in Early Detection of Diabetic Retinopathy

Author

Jin, Xu ; Guangshu, Hu ; Tianna, Huang ; Houbin, Huang ; Bin, Chen

Author_Institution

Dept. of Biomed. Eng., Tsinghua Univ., Beijing

fYear

2006

Firstpage

7762

Lastpage

7765

Abstract

To assess retinal changes in diabetic eyes at early stage of retinopathy, retinal responses were examined using multifocal ERG. Seven healthy subjects, 16 diabetics with no apparent retinopathy (NDR) and 9 diabetics who had background diabetic retinopathy (BDR) underwent multifocal ERG testing. The first slice of the second order kernel (K21) were extracted from multifocal ERG record and summed. Three major peaks (P1, N1 and P2) on the trace of summed K21 are evaluated across all subjects. With their amplitude and implicit time as 6 features, linear classifiers were built. These classifiers were used to discriminate eyes of control, NDR and BDR subjects. The classification error dropped significantly

Keywords

diseases; electroretinography; medical signal detection; medical signal processing; signal classification; diabetic eyes; early diabetic retinopathy detection; linear classifiers; multifocal ERG; retinal changes; Biomedical engineering; Blindness; Diabetes; Eyes; Hospitals; Kernel; Programmable logic arrays; Retina; Retinopathy; Testing; diabetic retinopathy; early detection; multifocal ERG; second order kernels;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1616312

Filename

1616312