Title :
Development of stable and tunable high-speed liquid jets in microscale for miniaturized and disposable flow cytometry
Author :
Huh, Dongeun ; Wei, Hsien-Hung ; Grotberg, James B. ; Takayama, Shuichi
Author_Institution :
Dept. of Biomed. Eng., Michigan Univ., Ann Arbor, MI, USA
fDate :
6/24/1905 12:00:00 AM
Abstract :
Presents an experimental investigation of the stability phenomena of an air-liquid two-phase microfluidic system in air-sheath-driven flow cytometry. High-speed thin liquid jets interacting with air-sheath flows and polymeric microfluidic channel walls show different flow behaviors in response to channel geometry, surface chemistry, and flow rates of liquid and air. We studied the variation of flow structure and stability of liquid jets in hydrophobic channels having different thickness to identify the effect of device geometry on microscale air-liquid two-phase flows
Keywords :
biological techniques; cellular biophysics; channel flow; jets; microfluidics; two-phase flow; air flow rates; air-liquid two-phase microfluidic system; air-sheath flows; air-sheath-driven flow cytometry; channel geometry; device geometry; flow structure; high-speed thin liquid jets; hydrophobic channels; liquid flow rates; microfluidic systems; microscale; microscale air-liquid two-phase flows; miniaturized disposable flow cytometry; polymeric microfluidic channel walls; stability phenomena; stable tunable high-speed liquid jets; surface chemistry; Biomedical engineering; Chemistry; Costs; Fluid flow; Geometry; Microfluidics; Polymers; Shape; Size control; Stability;
Conference_Titel :
Microtechnologies in Medicine & Biology 2nd Annual International IEEE-EMB Special Topic Conference on
Conference_Location :
Madison, WI
Print_ISBN :
0-7803-7480-0
DOI :
10.1109/MMB.2002.1002368
