Droplet-based Microtexture Biochip System for Triglycerides and Methanol Measurement

Author

Lin, Ming-Yu ; Yu, Chih-Sheng ; Hu, Yi-Chiuen ; Cheng, Shao-Chang ; Hu, Heng-Tsang

Author_Institution

Instrum. Technol. Res. Center, Nat. Appl. Res. Lab.

fYear

2005

fDate

6/27/1905 12:00:00 AM

Firstpage

530

Lastpage

533

Abstract

A droplet-based microfluidic system was developed for biochemical assays of triglycerides and methanol as potential applications in medical rapid diagnostics and food safety. We present a novel platform to manipulate biology reaction droplets with features of self-moving, self-mixing, and self-positioning toward the detection spot. The driving force comes from the gradient of surface tension force generated by the hydrophobic microtexture PDMS surface. We also demonstrate the experiments in water, and blood droplets running uphill to overcome the gravity. These findings support the ongoing works to develop the multifunctional biosensors in medicine and food safety

Keywords

bioMEMS; biochemistry; blood; drops; food safety; microfluidics; molecular biophysics; patient diagnosis; surface tension; biochemical assays; biology reaction droplets; blood droplets; food safety; hydrophobic microtexture PDMS surface; medical rapid diagnostics; methanol; microfluidic; microtexture biochip system; multifunctional biosensors; surface tension force; triglycerides; Cardiac disease; Cardiovascular diseases; Medical diagnostic imaging; Methanol; Microfluidics; Rough surfaces; Safety; Silicon; Surface roughness; Surface tension; PDMS; droplet-based microfluidic system; methanol; surface tension force; triglycerides;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1616465

Filename

1616465