Title :
Dynamic simulation of FDG-PET image based on VHP datasets
Author :
Qiao, Huiting ; Bai, Jing
Author_Institution :
Sch. of Biol. Sci. & Med. Eng., Beihang Univ., Beijing, China
Abstract :
The FDG-PET is an important imaging tool for early diagnosis and treatment of malignant tumor and functional disease. The main purpose of this work is to propose a method for simulation of dynamic FDG-PET images based on VHP datasets. First the tissue time-activity curves (TTAC) are simulated using compartment model with blood time-activity curve (BTAC), and then the noises of each voxel are estimated according to the activity countering and the scan duration. At last according to the obtained BTAC and TTACs, a set of corresponding values are assigned to the segmented VHP image together with the independent Gaussian noise respectively. Series dynamic FDG-PET images were simulated respectively for normal physiology and pathology. The results of this work may provide a novel simulation platform for the research of PET image processing.
Keywords :
Gaussian noise; blood; diseases; image segmentation; medical image processing; positron emission tomography; tumours; BTAC; FDG-PET; Gaussian noise; TTAC; VHP datasets; blood time-activity curve; functional disease; image processing; malignant tumor; tissue time-activity curve; Biochemistry; Cancer; Image segmentation; Kidney; Liver; Pancreas; Stomach; FDG; PET; VHP; simulation image;
Conference_Titel :
Complex Medical Engineering (CME), 2011 IEEE/ICME International Conference on
Conference_Location :
Harbin Heilongjiang
Print_ISBN :
978-1-4244-9323-4
DOI :
10.1109/ICCME.2011.5876723
