Title :
Enhanced Estimation of Motor Unit Number and Distribution Using Linear Least Squares Modeling
Author :
Krishnamachari, Srivathsan ; Kong, Xuan
Author_Institution :
NEUROMetrix Inc., Waltham, MA
Abstract :
MUNE methods estimate the typical motor unit (MU). The typical MU amplitude is divided into the compound muscle action potential (CMAP) amplitude to obtain the MUNE. A novel method is proposed in which the CMAP is modeled as a linear least squares (LLS) fit of the MU waveforms. The sum of the coefficients in the model is the motor unit number estimate. Each coefficient represents the count of the different MU estimates. The MU waveforms are clustered into groups with similar morphology and a representative waveform is calculated for each cluster. These representative waveforms are used in the LLS model
Keywords :
bioelectric potentials; least squares approximations; muscle; physiological models; waveform analysis; MUNE methods; compound muscle action potential; linear least squares modeling; motor unit distribution; motor unit number; representative waveforms; Amplitude estimation; Clustering algorithms; Least squares approximation; Least squares methods; Morphology; Muscles; Robustness;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616616
