Title :
Using Fractal Analysis to Characterize Cerebral Blood Flow and Immunohistopathology for Ischemic Stroke Research
Author :
Wu, Chunyan ; Zhao, Weizhao
Author_Institution :
Dept. of Biomed. Eng., Miami Univ., Coral Gables, FL
Abstract :
This paper presents an application of fractal analysis to characterization of global cerebral blood flow and immunohistopathology for ischemic stroke research on animal experiments. A brain´s vasculature has features of a branching tree and can be modeled as a fractal system. Fractal analysis can be then employed to assess cerebral blood flow and immuno-positives on a whole brain section. Fractal analysis on experimental data from three imaging modalities under ischemic and control status is presented in this paper. Statistic analysis and correlative study prove the effectiveness of fractal analysis. An analytical description of fractal parameters for experimental ischemic stroke has been achieved
Keywords :
brain; fractals; haemodynamics; statistical analysis; brain; fractal analysis; global cerebral blood flow; immuno-positives; immunohistopathology; ischemic stroke; statistic analysis; Animals; Biomedical engineering; Blood flow; Brain modeling; Data analysis; Equations; Fractals; Image analysis; Immune system; Statistical analysis; cerebral blood flow; fractal analysis; immunohistopathology; ischemic stroke;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616733