Title :
Multi-angle lensless holography for depth resolved high-throughput imaging of cells on a chip
Author :
Su, Ting-Wei ; Isikman, Serhan O. ; Bishara, Waheb ; Tseng, Derek ; Erlinger, Anthony ; Ozcan, Aydogan
Author_Institution :
Electr. Eng. Dept., Univ. of California, Los Angeles, CA, USA
Abstract :
A multi-angle lensfree holographic imaging platform capable of resolving the depth location of cells or microparticles on a chip, with an accuracy much greater than that allowed by the detection numerical aperture is presented. This multi-angle holographic imaging approach could be especially useful for improving the throughput of on-chip imaging and characterization of cells within microfluidic systems.
Keywords :
bioMEMS; biomedical optical imaging; cellular biophysics; holography; image resolution; lab-on-a-chip; microfluidics; depth resolved high-throughput imaging; microfluidic systems; microparticles; multiangle lensfree holographic imaging; numerical aperture detection; on-chip imaging; Apertures; Holographic optical components; Holography; Image resolution; Lenses; Light emitting diodes; Light sources; Lighting; Optical imaging; Sensor arrays;
Conference_Titel :
Photonics Society Winter Topicals Meeting Series (WTM), 2010 IEEE
Conference_Location :
Majorca
Print_ISBN :
978-1-4244-5240-8
Electronic_ISBN :
978-1-4244-5241-5
DOI :
10.1109/PHOTWTM.2010.5421957
