Title :
High-throughput microfluidics and ultrafast optics for in vivo compound/genetic discoveries
Author :
Yanik, Mehmet Fatih
Abstract :
We developed microfluidic and ultrafast optical technologies that enable high-throughput whole-animal neural regeneration studies. These technologies allow automated and rapid manipulation, and non-invasive immobilization of C. elegans for sub-cellular resolution two-photon imaging and femtosecond-laser nanosurgery.
Keywords :
bioMEMS; biomedical optical imaging; cellular biophysics; genetics; high-speed optical techniques; image resolution; laser applications in medicine; microfluidics; microorganisms; nanobiotechnology; neurophysiology; surgery; two-photon processes; C. elegans; femtosecond-laser nanosurgery; imaging resolution; microfluidics; neural regeneration; noninvasive immobilization; subcellular resolution; two-photon imaging; ultrafast optics; Animals; Biomedical optical imaging; Genetics; Image resolution; In vivo; Microfluidics; Optical imaging; Repeaters; Throughput; Ultrafast optics;
Conference_Titel :
Photonics Society Winter Topicals Meeting Series (WTM), 2010 IEEE
Conference_Location :
Majorca
Print_ISBN :
978-1-4244-5240-8
Electronic_ISBN :
978-1-4244-5241-5
DOI :
10.1109/PHOTWTM.2010.5421961
