DocumentCode
1614766
Title
Dynamics of FLT3 receptor under induced microwave stress
Author
Bojovschi, A. ; Chu, Z. ; Rowe, W.S.T.
Author_Institution
Electr. & Comput. Eng., RMIT Univ., Melbourne, VIC, Australia
fYear
2011
Firstpage
1498
Lastpage
1501
Abstract
The biological effect of electric fields on protein function and structure is a topic of increasing interest over the past few decades. With the proliferation of microwave devices the exposure to microwave radiation has become part of everyday life. The ubiquity of devices emitting electromagnetic radiation has highlighted concerns about the potential health effects. This work explores the dynamics of FLT3 under equilibrium conditions and under microwave stress. Equilibrium and non-equilibrium molecular dynamics are employed. The results show that intense microwave radiations can cause conformational changes in FLT3.
Keywords
bioelectric phenomena; biological effects of microwaves; biomagnetism; biomolecular effects of radiation; enzymes; molecular dynamics method; FLT3 receptor dynamics; biological effect-of-electric fields; electromagnetic radiation; induced microwave stress; microwave devices; microwave radiation; nonequilibrium molecular dynamics; potential health effects; proliferation; protein function; protein structure; Electric fields; Electromagnetic heating; Force; Microwave oscillators; Proteins; Stress; FLT3; microwave stress; molecular dynamics; protein conformational changes;
fLanguage
English
Publisher
ieee
Conference_Titel
Microwave Conference Proceedings (APMC), 2011 Asia-Pacific
Conference_Location
Melbourne, VIC
Print_ISBN
978-1-4577-2034-5
Type
conf
Filename
6174047
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