Title :
Boosting Based Classification of Event Related Potentials for Early Diagnosis of Alzheimer´s Disease
Author :
Stepenosky, Nicholas ; Topalis, Apostolos ; Syed, Hussein ; Green, Deborah ; Kounios, John ; Clark, Christopher ; Polikar, Robi
Author_Institution :
Dept. of Electr. & Comput. Eng., Rowan Univ., Glassboro, NJ
fDate :
6/27/1905 12:00:00 AM
Abstract :
With the number of the elderly population affected by Alzheimer´s disease (AD) rising, the need to find an accurate, inexpensive and non-intrusive procedure that can be made available to community healthcare providers for early diagnosis of Alzheimer´s disease is becoming more and more urgent as a major health concern. Several recent studies have looked at analyzing electroencephalogram signals through the use of wavelets and neural networks. In this study, multiresolution wavelet analysis, coupled with the ensemble of classifiers based boosting algorithm is used on the P300 component of the event related potentials (ERP) to determine the feasibility of the approach as a diagnostic tool for early diagnosis of AD. The technique and its promising initial results are presented
Keywords :
bioelectric potentials; diseases; electroencephalography; geriatrics; medical signal processing; neural nets; patient diagnosis; signal classification; wavelet transforms; Alzheimer disease; P300 component; boosting-based classification; classifiers; early diagnosis; electroencephalogram signals; event related potentials; healthcare; multiresolution wavelet analysis; neural networks; Algorithm design and analysis; Alzheimer´s disease; Boosting; Enterprise resource planning; Medical services; Neural networks; Senior citizens; Signal analysis; Signal resolution; Wavelet analysis; Alzheimer´s disease; ERP; P300; artificial neural networks; boosting; oddballparadigm; wavelet analysis;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616975