Surface Modification of Bio-MEMS Micro-device with Conducting Polymer - Studies with Rat Cardiomyocytes

Author

Lin, Chii-Wann ; Lee, Ming-Fung ; Yang, Yi-Fan ; Wu, Chau-Chung

Author_Institution

Inst. of Biomed Eng., Nat. Taiwan Univ., Taipei

fYear

2006

Firstpage

2619

Lastpage

2621

Abstract

Conducting polymer can modify device surface properties and incorporate biomolecules for immobilization by electropolymerization at the same time. We investigated a method for surface modification by electrochemically deposited polypyrrole onto surface of bio-MEMS micro device. We reported the effects of the numbers of CV cycle on the deposited film thickness and roughness in this paper. Furthermore, to prepare polypyrrole entrapment biomolecules on micro-device as a cell-culture substrate was demonstrated to promote cells adhesion

Keywords

bioMEMS; biosensors; cardiology; cellular biophysics; conducting polymers; microelectrodes; molecular biophysics; polymerisation; surface roughness; surface treatment; Au; CV cycle; bioMEMS microdevice; cell adhesion; cell-culture substrate; conducting polymer; device surface properties; electrochemically deposited polypyrrole; electropolymerization; film roughness; film thickness; polypyrrole entrapment biomolecules; rat cardiomyocytes; surface modification; Adhesives; Biosensors; Cardiology; Electrodes; Gold; Microelectrodes; Molecular biophysics; Polymers; Rough surfaces; Surface roughness; biomolecules; cell adhesion; electropolymerization; micro electrode; polypyrrole;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1617006

Filename

1617006