Title :
Alternative Base Calling Method for Resequencing Microarrays
Author :
Di, Xiaojun ; Cawley, Simon
Author_Institution :
Affymetrix Inc., Santa Clara, CA
Abstract :
Analysis of high density oligonucleotide arrays for resequencing requires methods which are highly robust and accurate. We introduce an alternative base calling method built upon ABACUS with the particular advantage of achieving a very low rate for false positive detection of heterozygotes
Keywords :
arrays; diseases; genetics; medical computing; molecular biophysics; ABACUS; alternative base calling method; false positive detection; heterozygotes; high density oligonucleotide arrays; resequencing microarrays; Couplings; DNA; Degenerative diseases; Genetics; Organisms; Pixel; Probes; Robustness; Sequences; Testing;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1617057
