• DocumentCode
    1617960
  • Title

    Systematic Reduction of a Bursting Neuron Model

  • Author

    Sorensen, Michael ; DeWeerth, Steve

  • Author_Institution
    Dept. of Biomed. Eng., Georgia Inst. of Technol., Atlanta, GA
  • fYear
    2006
  • Firstpage
    2922
  • Lastpage
    2925
  • Abstract
    We present our research in reducing the complexity of a conductance-based neural model. We utilize previously published techniques, as well as novel methods, to reduce a 14 state variable, conductance-based model of a bursting neuron to a 4 state variable hybrid integrate-and-fire model. The reduced model exhibits activity that is quantitatively similar to the complex model both in single-cell bursting mode, and when coupled to another neuron
  • Keywords
    bioelectric phenomena; neurophysiology; physiological models; bursting neuron model; complexity; conductance-based neural model; hybrid integrate-and-fire model; single-cell bursting mode; systematic reduction; Biological neural networks; Biological system modeling; Biomembranes; Calcium; Content addressable storage; Heart; Mechanical factors; Neurons; Reduced order systems; Voltage;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
  • Conference_Location
    Shanghai
  • Print_ISBN
    0-7803-8741-4
  • Type

    conf

  • DOI
    10.1109/IEMBS.2005.1617086
  • Filename
    1617086