Title :
Cortical Vascular Blood Flow Pattern By Laser Speckle Imaging
Author :
Li, Nan ; Tong, Shanbao ; Ye, Deliang ; Shin, Hyunchool ; Thakor, Nitish V.
Author_Institution :
Biomed. Eng. Dept., Johns Hopkins Univ. Sch. of Med., Baltimore, MD
Abstract :
The cortical vascular blood flow pattern is associated with the functional response in cerebral cortex. The pattern of the vascular blood flow can be used to study the spatiotemporal activities of the somatosensory center and the diagnosis of the focal stroke or ischemia. In this present study, temporal laser speckle analysis is used to obtain the cortical blood flow information. By centerline modeling method based on ridge tracking, we extracted the cortical vessels. By fusing with the laser speckle contrast results, we obtained the image of the cortical vascular blood flow pattern in which both the vessels and the blood velocity can be visualized
Keywords :
biomedical optical imaging; blood flow measurement; blood vessels; brain; flow visualisation; laser applications in medicine; speckle; blood velocity; centerline modeling method; cerebral cortex; cortical vascular blood flow pattern; focal stroke diagnosis; ischemia; laser speckle imaging; ridge tracking; somatosensory center; spatiotemporal activities; vessels; Blood flow; Brain modeling; Cerebral cortex; Data mining; Information analysis; Ischemic pain; Laser modes; Spatiotemporal phenomena; Speckle; Visualization;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1617189
