Title :
State-space analysis of ventricular/vascular coupling
Author_Institution :
Dept. of Electr. Eng., Rhode Island Univ., Kingston, RI, USA
Abstract :
The state-space analysis technique is applied to characterizing the time-varying interaction between the left ventricle and systematic vascular bed. An analog model of the circulatory system is developed. Pressure and flow waveforms in the system are computed by numerically integrating the five simultaneous state equations that represent the system dynamics. The model-predicted waveforms agree well with the psychological responses regarding the changes in peripheral resistance, vascular capacitance, viscoelastic loss, aortic valve stenosis, and intraaortic balloon pumping
Keywords :
cardiology; haemodynamics; physiological models; aortic valve stenosis; cardiac haemodynamics; circulatory system analog model; flow waveform; intraaortic balloon pumping; left ventricle; model-predicted waveforms; numerical integration; peripheral resistance; pressure waveform; psychological responses; simultaneous state equations; state-space analysis technique; system dynamics; systematic vascular bed; time-varying interaction; vascular capacitance; ventricular/vascular coupling; viscoelastic loss; Biological system modeling; Capacitance; Cardiovascular system; Circuits; Equations; Immune system; Predictive models; Time varying systems; Valves; Viscosity;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.95594
