Title :
Identifying Significant Genes from DNA Microarray Using Genetic Algorithm
Author :
Dheenathayalan, K. ; Ramsingh, J.
Abstract :
Microarray technology is used to monitor thousands of gene expression levels simultaneously and gained attention in recent years. Identifying significant Gene based on expression levels becomes important for diseases prognosis and diagnosis. Evolutionary algorithms like Genetic algorithms are used for finding optimized solutions. The focus of this paper is to apply genetic algorithms as preprocessing technique for identifying significant genes from microarray datasets. The identified genes can be used for analysis for diseases prediction using data mining tasks. The genetic algorithm is implemented using R language for the lymphoma microarray dataset.
Keywords :
bioinformatics; data mining; genetic algorithms; DNA microarray; R language; data mining; genes identification; genetic algorithms; lymphoma microarray dataset; preprocessing technique; Biological cells; Data mining; Gene expression; Genetic algorithms; Sociology; Statistics; Microarray; gene expression; genetic algorithm; machine learning; significant genes;
Conference_Titel :
Intelligent Computing Applications (ICICA), 2014 International Conference on
Conference_Location :
Coimbatore
DOI :
10.1109/ICICA.2014.10