Title :
Identification of left ventricular model parameters
Author :
Boom, Herman B K ; Wijkstra, Hessel
Author_Institution :
Dept. of Electr. Eng., Twente Univ., Enschede, Netherlands
Abstract :
Simulations with a model of left ventricular pressure generation consisting of time-varying elastance, resistance, series-elastance, and deactivation were fitted to pressure curves measured in the isolated rabbit ventricle. For constant ejection flows, a fit with a RMS error of 2.78 mmHg was obtained provided that deactivation was actually incorporated in the model. Deactivation was assumed to depend linearly on end ejection pressure. Resistance was found to be independent of volume
Keywords :
biomechanics; cardiology; parameter estimation; physiological models; RMS error; constant ejection flows; deactivation; end ejection pressure; isolated rabbit ventricle; left ventricular model parameters; left ventricular pressure generation; parameter identification; pressure curves; resistance; series-elastance; time-varying elastance; Catheters; Data acquisition; Data engineering; Difference equations; Finite difference methods; Pistons; Pressure measurement; Rabbits; Sampling methods; Transducers;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.95608
