Title :
Inductive detection of 4.5 μm superparamagnetic beads in a microfluidic device
Author :
Rzeszowski, S. ; Ferrier, G.A. ; Cabel, T. ; Nikolic-Jaric, M. ; Weber, D. ; Romanuik, S.F. ; Bridges, G.E. ; Thomson, D.J.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Manitoba, Winnipeg, MB, Canada
Abstract :
An inductance sensor based on a microwave interferometer capable of detecting magnetic markers in a microfluidic suspension is presented. The sensor can continuously detect micron-size superparamagnetic beads suspended in a microfluidic channel as they pass over a planar electrode loop. An estimated resolution of 1fH/√(Hz) was achieved, which is close to single particle resolution. The system relies solely on electronic detection, which enables it to be integrated onto an inexpensive and small-scale lab-on-a-chip platform.
Keywords :
inductive sensors; magnetic sensors; microfluidics; radiowave interferometers; superparamagnetism; suspensions; electronic detection; inductance sensor; inductive detection; magnetic marker detection; microfluidic channel; microfluidic device; microfluidic suspension; microwave interferometer; particle resolution; planar electrode loop; size 4.5 mum; superparamagnetic bead; Electrodes; Inductance; Magnetic resonance; Magnetic separation; Magnetic susceptibility; Microfluidics;
Conference_Titel :
Antenna Technology and Applied Electromagnetics & the American Electromagnetics Conference (ANTEM-AMEREM), 2010 14th International Symposium on
Conference_Location :
Ottawa, ON
Print_ISBN :
978-1-4244-5049-7
Electronic_ISBN :
978-1-4244-5050-3
DOI :
10.1109/ANTEM.2010.5552520