Title :
The feedforward-feedback system of the hypothalamus-pituitary-adrenal axis
Author :
Pornsawad, Pornsarp
Author_Institution :
Dept. of Math., Silpakorn Univ., Nakorn Prathom, Thailand
Abstract :
The hypothalamus-pituitary-adrenal axis is a complex system that is crucial for the survival of the organism stress. The mathematical model providing the qualitative behaviour of this endocrine system is needed. The mathematical model describing the feedforward-feedback mechanism of the hypothalamus-pituitary-adrenal axis is presented in this paper. The analysis via Hopf bifurcation reveals an important role of the composite delay time on the homeostasis and the pulsatility status of the hormone secretion in the body.
Keywords :
bifurcation; delays; feedback; feedforward; physiological models; Hopf bifurcation; complex system; composite delay time; endocrine system; feedforward-feedback mechanism; feedforward-feedback system; hormone secretion; hypothalamus-pituitary-adrenal axis; mathematical model; organism stress survival; qualitative behaviour; Bifurcation; Biochemistry; Delay effects; Delays; Limit-cycles; Mathematical model;
Conference_Titel :
Advances in Computing, Communications and Informatics (ICACCI), 2013 International Conference on
Conference_Location :
Mysore
Print_ISBN :
978-1-4799-2432-5
DOI :
10.1109/ICACCI.2013.6637379
