Title :
Quantitative biomechanical analysis of Drosophila embryos through the stages of embryogenesis using a sensorized human/robot cooperative interface
Author :
Cozen, Scott J. ; Zhang, Rui ; Shen, Yantao ; Xi, Ning ; Yi, Jingang
Author_Institution :
Dept. of Electr. & Biomed. Eng., Univ. of Nevada-Reno, Reno, NV
Abstract :
To better understand the biomechanical properties involved in Drosophila embryo research, this work presents a mechanical characterization of living Drosophila embryos through the stages of embryogenesis. Measurement of the mechanical properties of Drosophila embryos is implemented using a networked human/robot cooperative interface featuring a novel, in situ, and minimally invasive piezoelectric force-sensing tool with resolution in the range of muN. Penetration force profiles of the embryos at various stages of embryogenesis are reported. The Youngpsilas modulus, stiffness, and the mechanical impedance of the developing Drosophila embryos are quantitatively evaluated and presented alongside experimentally derived mathematical models.
Keywords :
Young´s modulus; biomechanics; biosensors; elastic constants; evolution (biological); human-robot interaction; medical computing; medical robotics; piezoelectric devices; user interfaces; Drosophila embryo; Young modulus; biomechanical analysis; embryogenesis stages; human-robot cooperative interface; mechanical impedance; penetration force profile; piezoelectric force sensing tool; stiffness; Embryo; Force measurement; Force sensors; Genetics; Humans; Impedance; Mechanical factors; Microinjection; Minimally invasive surgery; Robot sensing systems; Drosophila embryo; Young’s modulus; embryogenesis; mechanical impedance; microforce; polyvinylidene-fluoride (PVDF); stiffness;
Conference_Titel :
Biomedical Circuits and Systems Conference, 2008. BioCAS 2008. IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-4244-2878-6
Electronic_ISBN :
978-1-4244-2879-3
DOI :
10.1109/BIOCAS.2008.4696876
