DocumentCode :
1651026
Title :
Mini-Bioreactor for Protein Chips
Author :
Chang, Yaw-Jen ; Chang, Cheng-Hao
Author_Institution :
Dept. of Mech. Eng., Chung Yuan Christian Univ., Chung Li
fYear :
2008
Firstpage :
172
Lastpage :
175
Abstract :
This paper presents a novel design of mini-bioreactor with integrated functions, including temperature control, humidity control, and agitation control, for the biochemical reactions. The development of mini-bioreactors is important for the rapidly growing biochip researches. Since the structure of this module is simple, it offers many advantages over conventional ovens such as vast improvements in energy efficiency, enhancements in biochemical reactions, precise process control, and inexpensive fabrication cost. To verify the performance of mini-bioreactor, the immunoassay reactions were carried out using nitrocellulose protein chips. Under constant temperature and humidity, the effect of agitation on immunoassay reactions was investigated. It was discovered that agitation at lower vibrating frequency was indeed contributive to enhance the immunoassay reactions. It is a special function that the conventional ovens do not have.
Keywords :
bioMEMS; biochemistry; biological techniques; bioreactors; humidity control; lab-on-a-chip; microreactors; molecular biophysics; proteins; temperature control; MEMS technologies; agitation control; biochemical reaction enhancement; constant humidity; constant temperature; conventional oven comparison; humidity control; immunoassay reactions; integrated functions; lower vibrating frequency; mini-bioreactor performance; nitrocellulose protein chips; precise process control; temperature control; Costs; Energy efficiency; Fabrication; Frequency; Humidity control; Immune system; Ovens; Process control; Proteins; Temperature control;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
Type :
conf
DOI :
10.1109/ICBBE.2008.47
Filename :
4534927
Link To Document :
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