Title :
SERS sensing of cancer biomarkers
Author :
De Luca, A.C. ; Manago, S. ; Mariggio, S. ; Corda, D. ; Reader-Harris, P. ; Mazilu, Michael ; Di Falco, A.
Author_Institution :
Inst. of Protein Biochem., Naples, Italy
Abstract :
In this work, we establish the use a SERS biosensor based on gold fishnet as a label-free analytical technique for direct detection of glycerophosphoinositol (GroPIns). Here we demonstrate that with our approach we can quantitatively determine low concentration of GroPIns (200 nM) in multicomponent mixtures, with a high accuracy (up to 6%).
Keywords :
biomedical equipment; biosensors; cancer; enzymes; gold; molecular biophysics; nanofabrication; nanomedicine; nanoparticles; nanosensors; silver; surface enhanced Raman scattering; Ag; Au; SERS biosensor; SERS sensing; cancer biomarkers; direct glycerophosphoinositol detection; gold fishnet; label-free analytical technique; low-GroPlns concentration; multicomponent mixtures; Biomedical monitoring; Biosensors; Fingerprint recognition; Monitoring; Nanoparticles; Scattering; Standards; Biosensing; Cancer; Fishnet; Reproducibility; SERS;
Conference_Titel :
Photonics Technologies, 2014 Fotonica AEIT Italian Conference on
Conference_Location :
Naples
Print_ISBN :
978-8-8872-3718-4
DOI :
10.1109/Fotonica.2014.6843927
