Aminosilane-modified mesoporous oxidized silicon for in situ oligonucleotides synthesis and detection

Author

Terracciano, Matthew ; De Stefano, L. ; Rendina, I. ; Oliviero, Giorgia ; Piccialli, Gennaro ; Borbone, Nicola ; Rea, I.

Author_Institution

Inst. for Microelectron. & Microsyst., Nat. Council of Res., Italy

fYear

2014

fDate

12-14 May 2014

Firstpage

1

Lastpage

4

Abstract

Direct solid phase of oligonucleotides (ONs) requires high chemical stability of the support material. In this work, we investigate the passivation ability of porous oxidized silicon multilayered structures by two aminosilane compounds, APTES and APDMES, for the realization of a label-free ON optical biosensor.

Keywords

DNA; biochemistry; biosensors; electrochemical sensors; elemental semiconductors; mesoporous materials; molecular biophysics; multilayers; optical sensors; oxidation; passivation; silicon; Si; aminosilane compounds; aminosilane-modified mesoporous oxidized silicon; chemical stability; in situ oligonucleotides detection; in situ oligonucleotides synthesis; label-free ON optical biosensor; passivation; porous oxidized silicon multilayered structures; Bioinformatics; Biosensors; DNA; Genomics; Maximum likelihood estimation; Probes; Resists; DNA synthesis; functionalization; porous silicon; surface stability;

fLanguage

English

Publisher

ieee

Conference_Titel

Photonics Technologies, 2014 Fotonica AEIT Italian Conference on

Conference_Location

Naples

Print_ISBN

978-8-8872-3718-4

Type

conf

DOI

10.1109/Fotonica.2014.6843946

Filename

6843946