Title :
FT-IR microspectroscopy of cisplatin loaded PLGA nanoparticles
Author :
Portaccio, Marianna ; Menale, Ciro ; Diano, Nadia ; Mita, Damiano G. ; Lepore, Maria
Author_Institution :
Dipt. di Med. Sperimentale, Seconda Univ. di Napoli, Naples, Italy
Abstract :
Biodegradable polymer nanoparticles have recently received considerable attention for drug delivery. One of the most investigated system is represented by cisplatin-loaded poly-(D, L-lactic-co-glycolic)acid (PLGA) nanoparticles. FT-IR microspectroscopy has been used for characterizing these particles. In addition an univariate analysis procedure has been adopted for interpreting experimental results when the spectrum modifications are relatively weak.
Keywords :
Fourier transform spectra; biodegradable materials; biomedical materials; drug delivery systems; drugs; infrared spectra; nanomedicine; nanoparticles; nanophotonics; polymer blends; FT-IR microspectroscopy; biodegradable polymer nanoparticles; cisplatin loaded PLGA nanoparticles; drug delivery; poly-(D, L-lactic-co-glycolic)acid; spectrum modifications; Atmospheric measurements; Nanoparticles; Particle measurements; FT-IR microspectroscopy; PLGA nanoparticles; cisplatin; drug delivery; univariate analysis;
Conference_Titel :
Photonics Technologies, 2014 Fotonica AEIT Italian Conference on
Conference_Location :
Naples
Print_ISBN :
978-8-8872-3718-4
DOI :
10.1109/Fotonica.2014.6843959
