Title :
Label-free biosensors based on athermal silicon-on-insulator waveguides and a harmonic dithering technique
Author :
Kim, Kangbaek ; Pafchek, Robert M. ; Koch, Thomas L.
Author_Institution :
Dept. of Electr. & Comput. Eng., Lehigh Univ., Bethlehem, PA, USA
Abstract :
We report a new high-sensitivity biosensor using athermal TM-mode SOI resonators with bulk and surface detection limits of 4.7×10-7 RIU and ~100fg/mm2. Simple DFB harmonic dithering feedback techniques obviate spectrometers and tunable lasers.
Keywords :
bioMEMS; biosensors; elemental semiconductors; enzymes; microsensors; molecular biophysics; optical resonators; optical sensors; optical waveguides; sensitivity; silicon; silicon-on-insulator; DFB harmonic dithering feedback techniques; Si; TM-mode SOI resonators; athermal silicon-on-insulator waveguides; biotin-streptavidin system; bulk detection limits; harmonic dithering technique; high-sensitivity biosensor; label-free biosensors; surface detection limits; Biosensors; Harmonic analysis; Optical ring resonators; Optical surface waves; Optical waveguides; Power harmonic filters; Temperature measurement;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2012 Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-4673-1839-6
