Title :
Implantable resorbable micro-prism arrays for real-time drug release monitoring
Author :
Tao, H. ; Siebert, S.M. ; Pritchard, E.M. ; Sassaroli, A. ; Panilaitis, B. ; Brenckle, M.A. ; Amsden, J.J. ; Levitt, J.M. ; Fantini, S. ; Kaplan, D.L. ; Omenetto, F.G.
Author_Institution :
Dept. of Biomed. Eng., Tufts Univ., Medord, MA, USA
Abstract :
We present a free-standing micro-prism array device entirely constituted by silk protein showing enhanced optical reflectivity, which can be used to monitor drug delivery while slowly degrading to surrounding tissues with no adverse biological effects.
Keywords :
bioMEMS; biodegradable materials; biological tissues; biomedical equipment; biomedical optical imaging; drug delivery systems; drugs; micro-optics; optical arrays; optical prisms; patient monitoring; proteins; reflectivity; biodegradation; drug delivery monitoring; free-standing microprism array device; implantable resorbable microprism arrays; optical reflectivity; real-time drug release monitoring; silk protein; tissues; Biomedical optical imaging; Drugs; Monitoring; Optical devices; Optical films; Optical reflection; Optical scattering;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2012 Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-4673-1839-6
