• DocumentCode
    1664198
  • Title

    Parallelisation of IBD computation for determining genetic disease map

  • Author

    Rizk, Nouhad J.

  • Author_Institution
    Comput. Sci. Dept., Notre Dame Univ., Zouk-Mosbeh, Lebanon
  • fYear
    2003
  • Abstract
    A number of software packages are available for the construction of comprehensive human genetic maps. In this paper we parallelize the widely used package Genehunter. We restrict our attention to only one function of the package, namely the computations of Identity By Descent (IBD) genes of a family. We use a master-slave model with the Message Passing Interface (MPI) parallel environment. Our tests are done on two different architectures: a network of workstations and a shared memory multiprocessor. A new and efficient strategy to classify the parallelization of genetic linkage analysis programs results from our experiments. The classification is based on values of parameters which affect the complexity of the computation.
  • Keywords
    biology computing; computational complexity; genetics; message passing; parallel architectures; parallel programming; shared memory systems; software packages; workstation clusters; Genehunter; IBD genes; Identity By Descent genes; MPI parallel environment; Message Passing Interface; comprehensive human genetic maps; computation complexity; family; genetic linkage analysis programs; master-slave model; network of workstations; parallel architectures; parallelization; shared memory multiprocessor; software packages; Computer architecture; Concurrent computing; Diseases; Genetics; Humans; Master-slave; Message passing; Packaging; Software packages; Testing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Parallel and Distributed Processing Symposium, 2003. Proceedings. International
  • ISSN
    1530-2075
  • Print_ISBN
    0-7695-1926-1
  • Type

    conf

  • DOI
    10.1109/IPDPS.2003.1213293
  • Filename
    1213293