Effect of collagen treatment on the biocompatibility of β-Ti-14Mo-3Nb-3Al-0.2Si alloy

Titanium and Titanium alloys have been widely used in aerospace and automotive industries and medical applications due to their high strength-to-density ratio, excellent fatigue and corrosion resistances. Especially metastable ß titanium alloys are increasingly attractive for commercial use in high strength structural components because of their excellent cold formability. Some ß titanium alloys are being used as bone implants under biomechanical loading condition because of its excellent biocompatibility and mechanical properties. An essential requirement for an artificial material to bond to living bone is the formation of a bonelike apatite layer on its surface in body environment. The formation of a bone-like apatite surface layer can be reproduced in an acellular simulated body fluid (SBF) with ion concentration nearly equal to those of inorganic part of human blood plasma. In this study, biomimetic apatite deposition behaviors in various SBF conditions and stress-strain responses of Ti-15Mo-3Nb-3Al-0.2Si alloy were examined.