Title :
Preparation and characterization of polymeric micelles consisting of poly(propylene glycol) and poly(caprolactone) as a drug carrier
Author :
Lee, Sang Hyo ; Oh, Jae Min ; Son, Jin Soo ; Lee, Jae Hyeok ; Kim, Jae Il ; Kwon, Doo Yeon ; Lee, Bong ; Kim, Jae Ho ; Kim, Moon Suk
Author_Institution :
Dept. of Mol. Sci. & Technol., Ajou Univ., Suwon, South Korea
Abstract :
We describe the synthesis and solution properties of PCL-b-PPG-b-PCL triblock copolymers via ring-opening polymerization (ROP) of ¿-caprolactone (CL) monomer initiated at the hydroxyl end group of poly(propylene glycol) (PPG) using HCl-Et2O as a monomer activator.
Keywords :
biochemistry; biomedical materials; chemical analysis; colloids; drugs; materials preparation; polymer blends; polymer solutions; polymerisation; drug carrier; hydroxyl end group; micelle concentration; poly(caprolactone); poly(propylene glycol); polymeric micelles; ring-opening polymerization; triblock copolymers; ¿-caprolactone monomer; Biodegradable materials; Drug delivery; Glass; Heating; Moon; Nitrogen; Nuclear magnetic resonance; Polymers; Protons; Spectroscopy;
Conference_Titel :
Nanoelectronics Conference (INEC), 2010 3rd International
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-3543-2
Electronic_ISBN :
978-1-4244-3544-9
DOI :
10.1109/INEC.2010.5424831
