Title :
Ultrasensitive, optofluidic biomolecular fluorescence detection using flow-through, multi-hole capillary
Author :
Guo, Yunbo ; Oo, Maung Kyaw Khaing ; Hoyt, David ; Lamar, Dax ; Reddy, Karthik ; Fan, Xudong
Author_Institution :
Dept. of Biomed. Eng., Univ. of Michigan, Ann Arbor, MI, USA
Abstract :
A novel fluorescence detection platform is proposed and developed using a flow-through, multi-hole capillary, which provides integrated micro-/nanofluidic channels for fast, efficient analyte delivery and large surface area for ultrasensitive (sub-femotomolar) biomolecular detection.
Keywords :
bioMEMS; biosensors; capillarity; enzymes; fibre optic sensors; fluorescence; micro-optomechanical devices; microchannel flow; microsensors; molecular biophysics; nanofluidics; nanosensors; sensitivity; analyte delivery; enzyme-linked immunosorbent assay; fibre optic sensors; flow-through capillary; microfluidic channels; multihole capillary; nanofluidic channels; surface area; ultrasensitive optofluidic biomolecular fluorescence detection; ultrasensitive subfemotomolar biomolecular detection; Fluorescence; Nanobioscience; Optical surface waves; Photonic crystal fibers; Sea measurements; Sea surface; Sensors;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2012 Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-4673-1839-6
